The role of the MPFC areas in the behavioral response associated with fear is discussed.
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The medial prefrontal cortex (MPFC) reliably activates in social cognition and reward tasks.
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We found ES-associated up-regulation of brain-derived neurotrophic factor in amygdala as well as in mPFC.
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Social investigation and plus-maze open arm exploration increased in MPFC damaged animals relative to sham ones.
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At the same time, sleep induces a memory-related functional connectivity between the hippocampus and the mPFC.
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Interestingly, however, no regions of the MPFC were found to be responsive to social information independently of valence.
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Behavioral effects of a medial prefrontal cortex (MPFC) transection were assessed in animal tests of anxiety.
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These results generalized from one task to the other, suggesting a new axis of functional organization within MPFC.
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These findings reveal a previously unsuspected division of function among CA1 neurons that project directly to the mPFC.
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Cognitive evaluation of emotional stimuli involves a network of brain regions including the medial prefrontal cortex (mPFC).
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The results suggest that the alteration within the BLA subsequently resulted in a form of trans-regional metaplasticity in the mPFC.
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Collectively, these data indicate that the claustrum has functional connections with mPFC and MD-thalamus that are significantly lessened by anesthesia.
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Medial prefrontal cortex (MPFC) activation during message exposure reliably predicts downstream behavior, but past work has been largely atheoretical.
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Reversible mPFC inactivation using GABA agonist muscimol resulted in decreased timing precision, with no effect on timing accuracy and scalar timing.
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Moreover, abstinence from alcohol was associated with a functional disconnection of the mPFC and CeA but not mPFC and nucleus accumbens.
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We therefore hypothesized that prefrontal 5-HT 2A receptors can modulate DA transmission through excitatory mPFC-VTA inputs.