1
These results have implications for the design of multivalent vaccines.
2
Furthermore, to reduce the burden of vaccination, the development of multivalent vaccines is highly desirable.
3
Our study suggests that multivalent vaccines may be more suitable in this setting, especially for HIV-infected individuals.
4
The use of such multivalent vaccines did not show overt immune interference in comparison with monovalent vaccines.
5
Collectively, our results support previous reports about the potential benefit of EV-A71 vaccine but highlight the necessity of multivalent vaccines to control HFMD.