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1However, the biological function of the mutant proteins remains to be elucidated.
2GFP-tagged mutant proteins were unable to localize to sites of polarized growth.
3By Western analysis, all three mutant proteins are expressed in yeast.
4Structural modeling of the wild and mutant proteins was also performed.
5The mutant proteins were produced in normal amounts in blood and fibroblastic cells.
6However, the truncated and mutant proteins exerted only partial effects.
7Furthermore, the mutant proteins were able to bind RNA with approximately 8-fold higher affinity.
8Many of the mutant proteins have increased turnover in vivo and decreased thermal stability.
9Immunofluorescence analysis demonstrated increased intracellular retention of the mutant proteins.
10In addition, the mutant proteins preferentially localized to the nucleus.
11Structural predictions of the wild-type and mutant proteins were conducted.
12Thus, one potential strategy for dealing with these mutant proteins is to enhance their degradation.
13Deletion and point mutation of this part resulted in the cytoplasmic translocation of mutant proteins.
14Although some of the BAF mutant proteins efficiently bound DNA, others were defective for binding.
15Structural changes of the mutant proteins were modeled.
16Simultaneous expression of mutant proteins lacking these residues results in complete uncoupling from the cell cycle.
Aquesta col·locació està formada per:
Mutant proteins a través del temps
Mutant proteins per variant geogràfica