Significats de n-terminal acetylation en anglès

N-terminal acetylation is a common protein modification in eukaryotes associated with numerous cellular processes.

N-terminal acetylation is an abundant modification influencing protein functions.

N-terminal acetylation has several different roles in the cell, including altering protein stability and degradation, protein localization and protein-protein interactions.

N-terminal acetylation or incorporation of D-amino acids in the GPGRAF sequence of this SPC resulted in significant loss of activity.

Peptide binding is abrogated by N-terminal acetylation of the peptide or loss of the positive charge of the N-terminal residue.

In particular, cell size and maximum population size were highly correlated to the degree of N-terminal acetylation of the alcohol dehydrogenase.

N-Terminal acetylation clearly plays a role in Ogden syndrome, thus revealing the in vivo importance of N-terminal acetylation in human physiology and disease.