She had expected people higher in neuroticism to have the most problems.

High neuroticism and difficulties increased risk, even without a stressful life event.

Distributed reductions in cortical gray matter volumes were associated with increased neuroticism.

Meta-analytic results highlighted the importance of Big Five neuroticism, extraversion, and conscientiousness.

Higher baseline neuroticism was associated with poorer outcome across treatment conditions.

Without both high neuroticism and difficulties, stressful life events did not increase risk.

Higher educational attainment, treatment and neuroticism were also correlated with more absenteeism days.

These results suggest common SNP variation does not strongly influence neuroticism.

In the study protocol, neuroticism was defined as the primary outcome.

Lastly, we examined the contribution of a potential pre-existing vulnerability due to neuroticism.

In fact, after six weeks of microdosing, a small increase in neuroticism was noted.

Stressful early family environments and neuroticism were significantly associated with shorter preinternship telomere length.

Negative affect was predicted by neuroticism and sense of coherence.

Objective: Stressful life events, long-term difficulties, and high neuroticism are established risk factors for depression.

Individuals with TLE showed significantly higher neuroticism, with no significant differences on the other traits.

Severity of depression and high neuroticism scores were the best predictors of persistent depressive symptoms.