Significats de neutralizing activity en anglès

Significant correlation was observed between neutralizing activity and oligomeric gp120 binding activity.

Testing of purified immunoglobulin confirmed that the neutralizing activity was antibody mediated.

The HIV neutralizing activity was evaluated with a neutralization assay.

Antibodies to it appear to react primarily with carbohydrate and do not demonstrate neutralizing activity.

A clear trend of increase in DIII-specific neutralizing activity was observed over the course of infection.

Elicitation of antibodies with potent and broad neutralizing activity against HIV by immunization remains a challenge.

None of the treatment-emergent ADA showed cross-reactivity toward native granulocyte-colony stimulating factors or exhibited neutralizing activity against tbo-filgrastim.

The neutralizing activity of these serum samples could not be inhibited by peptide 313-327.

While titers increased rapidly after boosting, avidity and neutralizing activity matured more slowly over a 6-month period following protein boosting.

Based on its broad and potent neutralizing activity, further development of anti-V3 scFv for therapeutic and preventive strategies is warranted.

This protection significantly correlated with the in vitro neutralizing activity of the antisera but not with their corresponding ELISA titers.

Importance: There are very few individuals able to mount broadly neutralizing activity (bNA) close to the first year postinfection.

Our data suggest that HIV-1 broadly cross- neutralizing activity is variable over time and associated with detectable viremia and partial B-cell restoration.

The impact of overall findings on the potential use of serum neutralizing activity as a correlate of protective immunity is discussed.

We examined the in vivo efficacy of the human monoclonal antibody m336, which has high neutralizing activity against MERS-CoV in vitro.

However, this reduction was not simply a reflection of virus neutralizing activity, since not all antibodies which neutralized in vitro were protective.