Significats de npc cells en anglès

CircSERPINA3 inhibition significantly attenuated the invasion and proliferation abilities of NPC cells.

In contrast, treatment with ZD6474 strongly inhibited the invasion and migration of NPC cells.

The knockdown of CASC9 evidently suppressed migration and invasion but promoted apoptosis in NPC cells.

Events underlying the switching of lytic to latent EBV infection in NPC cells are largely undefined.

Conclusion: Our data indicate that T83 exhibits potent inhibitory activity in NPC cells and induces radiotherapy sensitivity.

Mechanically, Twist1 could promote the accumulation of DNA damage repair and inhibit the apoptosis of NPC cells.

The gene is located at 3p21 which is commonly deleted in NPC cells.

We show that MAOA is down-regulated in primary NPC tissues and its down-regulation enhances the migration of NPC cells.

However, there are limited studies regarding its effects on NPC cells, and its mechanism of action in NPC remains unknown.

The role of altered energy metabolism in host cells in modulating latent and lytic EBV infection in NPC cells is unclear.

Despite the cytotoxicity exhibited by NPC cells following radiotherapy, the invasion and migration of NPC cells was found to be unaffected.

We further showed that the silence of ATM expression by ATM-targeted siRNA could enhance the radiosensitivity in LMP1 positive NPC cells.

TR cells exhibited stronger drug efflux than parental NPC cells, leading to the reduction of intracellular drug concentrations and drug insensitivity.

Knockdown of AP-2a also significantly suppressed cell proliferation in NPC cells in vitro and tumor growth in a NPC xenograft mouse model.

More importantly, we demonstrated that the systemic delivery of lentivirus-mediated miR-101 abrogated the lung metastatic colonization formation of NPC cells without obvious toxicity.

Molecular events and alterations of cell metabolism are likely to play crucial roles in switching EBV infection from lytic to latent in NPC cells.