1
Measures: Cranial MRI was obtained at baseline and approximately 2 years later.
2
Plasma catecholamine levels were obtained at baseline, peak exercise, and during recovery.
3
Serum samples were obtained at baseline visit and after three months of aTNF treatment.
4
Similar glucose concentrations were obtained at baseline and at exhaustion during all treatment regimens.
5
Vastus lateralis biopsies were obtained at baseline and week 16.
6
Dietary intake was assessed by food frequency questionnaires obtained at baseline and during follow-up.
7
Standardized knee radiographs were obtained at baseline and 24 months.
8
Cone-beam Computed Tomography (CBCT) scans were obtained at baseline and at 16 weeks.
9
Indocyanine-green angiography was obtained at baseline and 3 months.
10
Smoking status and history of smoking were obtained at baseline and in all subsequent questionnaires.
11
Oral cavity mucosal biopsies and whole blood were obtained at baseline and after 12 weeks.
12
MRI data sets of the brain were obtained at baseline and after eight weeks follow-up.
13
Measurements: Data on thyroid status, aortic atherosclerosis, and history of myocardial infarction were obtained at baseline.
14
Risk factor data on the family's socioeconomic status, distance to water, and hygiene practices were obtained at baseline.
15
Measures obtained at baseline, 3 months, 6 months and 1 y.
16
Measures will be obtained at baseline, 6 months, and 12 months after randomization.
