1
The Rgr portion of the fusion was demonstrated to contain the oncogenic activity.
2
ChoKa1 displays its oncogenic activity through activation of specific signaling pathways that influence on cell proliferation and survival.
3
In this issue of Cancer Cell, demonstrate a novel mechanism for the oncogenic activity of MLL chimeric proteins.
4
These data provide further evidence for a direct oncogenic activity of hTERT not based on the inhibition of CIN.
5
This work defines HACE1 as a crucial regulator of the oncogenic activity of RAC-family GTPases in lung cancer development.
6
The unique dependence on self-association for E2A-PBX1 oncogenic activity suggests potential approaches for mechanism-based targeted therapies.
7
Although studies have shown that TRAF6 has oncogenic activity, the role of TRAF6 in melanoma is unclear.
8
Hence, our findings support that netrin-1 exerts oncogenic activity through YAP signaling, providing a mechanism coupling extracellular signals to the nuclear YAP oncogene.
9
To examine the mechanisms by which Tcl1 protein exerts its oncogenic activity in B cells, we performed proteomics experiments to identify its interacting partners.
10
We propose that heightened oncogenic activity in early cell divisions activates a growth-suppressive DDR that is attenuated by viral latency products to induce cell immortalization.
11
Clinical use of these findings hinges on isolating the oncogenic activity within the 17-92 cluster and defining its relevant target genes.
12
The oncogenic activity of the three chromosomal translocations is linked by the physiological role of BCL10 and MALT1 in antigen receptor-mediated NFkappaB activation.
13
The RAR ligands up-regulated many tumor-suppressive genes and down-regulated multiple genes with oncogenic activities.
14
This study will expand our understandings of the oncogenic activities of human papillomaviruses and lncRNAs.
15
WT1 can manifest both tumour suppressor and oncogenic activities, but the reasons for this are not yet clear.
16
We propose that the tumor suppressor activities of the inhibin alpha subunit dominate in non-malignant tissue, but its oncogenic activities emerge during tumorigenesis.
