Recently, a new family of transporters, named OCT ( organiccation transporters) has been described.
2
These results indicate that the influx transport for amantadine across the BBB involves a proton-coupled organiccation antiporter.
3
Transport rates by organiccation transporters (OCTs) were up to three-fold higher than those of OATs.
4
No significant correlations of valacyclovir pharmacokinetic parameters with PEPT1 and with organiccation or anion transporter expression levels were observed.
5
Because dolutegravir inhibits the renal transporter organiccation transporter 2, reduced tubular secretion of creatinine leads to non-progressive increases in serum creatinine.
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Here we report that there is significant association between rheumatoid arthritis and the organiccation transporter gene SLC22A4 (P = 0.000034).
7
This phenomenon indicates that the organiccations, which adjust the reaction pH values, can induce different dimensional inorganic frameworks.
8
In ion substitution experiments the current could be carried nonselectively by most cations, including divalent and organiccations, but not by chloride or sulfate ions.
9
Organiccation transporters function primarily in the elimination of cationic drugs, endogenous amines, and other xenobiotics in tissues such as the kidney, intestine, and liver.