Significats de organoid model en anglès

The organoid model helps identify functional elements that may drive disease onset.

In an organoid model of IBD, the new agonist increases expression of LRH-1-controlled steroidogenic genes and promotes anti-inflammatory gene expression changes.

In this study, we employed a three-dimensional organoid model of human pancreatic cancer to characterize the molecular alterations critical for invasion.

Thus, our organoid models reveal human oligodendrogenesis with ventral and dorsal origins.

Organoids models have been applied to pancreatic cancer research and offer a promising platform for precision medicine approaches.

Combination treatment with small-molecule inhibitors of both transcription factors resulted in synergistic decreases in cell growth in cell lines and patient-derived organoid models.