Significats de orotic acid en anglès

Age did not alter responses of rats to 1% dietary orotic acid.

The total NS and orotic acid contents did not differ significantly between the 2 species.

The influences of diet composition, age and sex on alterations induced by orotic acid were also studied.

Effects of 1% dietary orotic acid on lipid metabolism were examined in rats, mice, hamsters and guinea pigs.

Ten daily injections of growth hormone altered neither UMP synthase activity in erythrocytes nor orotic acid concentrations in milk and urine.

Inability to stimulate OTC under CR led to a failure to reduce orotic acid levels, a known outcome of OTC deficiency.

This hypothesis is supported by parallel changes in AADA gene expression in animals with insulin-deficient diabetes and following treatment with orotic acid.

The responses of mice to orotic acid were opposite to those of rats; liver lipid was decreased, and serum cholesterol was increased.