The structure also shows an atypical oxyanion hole and a partially collapsed S1 specificity pocket.
2
The rising pH converts oxyanion sorption sites from positive to negative releasing As (and Mo) to pore waters.
3
X-ray crystal structures of L29I PFE with and without bound acetate show an unusual mixture of two different oxyanion loop conformations.
4
The oxyanion hole hydrogen bonds provide additional stabilization for acyl-ester bond in the acyl-enzyme than for scissile peptide bond of the Michaelis complex.
5
Microbial oxygen production during reduction of oxyanions may enhance biodegradation of pollutants under anoxic conditions.
6
These structures also show that tetrahedral oxyanions bind at a novel secondary site and function to coordinate the PTP, WPD, and E loops.