Meanings of pathological hallmark in anglès

The accumulation of protein aggregates is a common pathological hallmark of many neurodegenerative diseases.

Drusen accumulation is the major pathological hallmark common to both dry and wet AMD.

Foam cell formation due to excessive accumulation of cholesterol by macrophages is a pathological hallmark of atherosclerosis.

While aggregation is a pathological hallmark of HD and related polyQ expansion diseases, the role of aggregates has been disputed.

The pathological hallmark of cystic fibrosis (CF) chronic inflammatory response is the massive neutrophil influx into the airways.

Small hydrophobic ligands identifying intracellular protein deposits are of great interest, as protein inclusion bodies are the pathological hallmark of several degenerative diseases.

Aggregation of tau into fibrillar structures within the CNS is a pathological hallmark of a clinically heterogeneous set of neurodegenerative diseases termed tauopathies.

Brain deposition of amyloid-beta (A beta) is a pathological hallmark of Alzheimer disease (AD) but A beta is also detected in non-demented elderly individuals.

Neurofibrillary tangles are among the pathological hallmarks of Alzheimer's disease.

Amyloid plaques are one of the pathological hallmarks of Alzheimer's disease (AD).

One of the major pathological hallmarks of AD is the brain deposition of amyloid beta-peptide (Abeta).

Accumulating evidence has demonstrated that immune memory occurs in microglia, which has a significant impact on pathological hallmarks of neurological diseases.

We recently generated a novel genetically engineered pig model reflecting pathological hallmarks of human DMD better than the widely used mdx mouse.

However, it is the fibrillar Aβ form that aggregates as amyloid plaques and cerebral amyloid angiopathy, which serve as pathological hallmarks of AD.

Thrombin is elevated in the AD brain, and thrombin signaling has been linked to both tau and amyloid beta, pathological hallmarks of the disease.

It is characterized by pathological hallmarks such as extracellular deposits of amyloid plaques as well as intracellular neurofibrillary tangles and a progressive loss of neurons.