The most prominent flaws were measurement bias, limited sample size, and patient recruitment.

Our institute also participates in adjuvant clinical trials, but slow patient recruitment is a problem.

Discussion: This study will provide insight in barriers and facilitators for successful patient recruitment in trials.

This could especially improve the comparability of imaging end points and facilitate patient recruitment in clinical trials.

In the meantime, patient recruitment for the study had been put on hold, an Ascot spokeswoman said.

The primary endpoint of the feasibility phase is to assess the rate of patient recruitment and randomisation.

Heritability is essential for understanding the biological causes of disease but requires laborious patient recruitment and phenotype ascertainment.

Measures included patient recruitment, mechanism of injury, injury severity score, alcohol use characteristics, and patients' opinion of the computer program.

Strategies to increase HIV physician's patient recruitment would be needed if DARE were to be implemented in anal cancer screening.

One the contrary, certain counter effects have been observed: modification in patient recruitment, higher-risk patients being referred to hospitals with unpublished mortality rates.

Conclusions: This paper adds to the methodological evidence for improving patient recruitment in different settings, with a focus on qualitative research in emergency departments.

The proportions of trials registered after the end of patient recruitment were 55%, 58% and 62% in 2009, 2010 and 2011 respectively.

Patient recruitment was via general practitioner dementia registers.

Setting: Patient recruitment and data collection were performed in nine primary care centres in three main regions in Sweden.