The current studies identify a new role for Akt in CNS myelination.
2
Conclusion: The Akt-Caspase 3 signal pathway may be involved in these processes.
3
We compared this effect by Western Blot analysis of Akt protein expression.
4
Moreover, the CG treatment down-regulated the phosphorylation levels of Akt and GSK3β.
5
Methods: Akt-2 expression was analyzed by western-blotting and Q-PCR in cell lines.
1
All of these changes involve long-term activation of the proteinkinaseAkt.
2
The host cells demonstrated increased phosphorylation of major survivor proteinkinaseAKT correlating with reduced toxicity of the mutant in comparison with Sterne.
1
Activation of Akt, or proteinkinaseB, is frequently observed in human cancers.
2
Both agents lowered proteinkinaseB activity, but this was not mediated by inhibiting phosphoinositide 3-kinase.
3
We found a high level of proteinkinaseB (AKT) phosphorylation after 6 h of cold exposure.
4
The Akt ( proteinkinaseB) kinase is a key player in transduction of antiapoptotic and proliferative signals in T cells.
5
A lower level of phosphorylated proteinkinaseB was observed in PFKFB3-knockdown endothelial cells, which was accompanied by a decrease in intracellular lactate.
Ús de pkb en anglès
1
This makes inhibition of PKB signaling pathway a promising strategy for cancer therapy.
2
Experiments were performed in MER-Akt cells to investigate the role of PKB in controlling mTOR.
3
PKB's support will add weight to his candidacy.
4
NU says it communicates regularly with PKB but has no intention of intervening in policy affairs.
5
These results demonstrate that PKB activity in early G1 phase is required to prevent the induction of apoptosis.
6
He opted for the small PKB party, where he is now deputy head, because of its pluralistic bent.
7
Of these parties, PKB did the best because it recruited several non-Muslim candidates to broaden its appeal, politicians said.
8
Regarding the OAG's actions, PKB spokesman Pascal Dubey said the bank had approached the authorities in the first place.
9
PKB said in a statement the FINMA decision would have no impact on the smooth functioning of the bank.
10
These cells express a PKB-mutant estrogen receptor fusion protein that is activated when the cells are exposed to 4-hydroxytamoxifen.
11
PKB won the most votes of the five Islamic-based parties in April's parliamentary elections, which set the stage for the presidential poll.
12
Our findings support the conclusion that insulin activates mTOR by promoting phosphorylation of the protein via a signaling pathway that contains PKB.
13
The moderate National Awakening Party (PKB), which is part of the Jokowi coalition, is on track to get 9 percent of the vote.
14
These data were supported by the fact that mutation of residue S473 of PKB to alanine did not prevent it from being activated by forskolin.
15
The highlights include the discovery of a protein kinase required for the 3-phosphoinositide-dependent activation of PKB and the identification of several physiological substrates for PKB.
16
Involvement of PKB in DENA-induced HCC was confirmed by the observed decrease in cell proliferation in DENA-HCC cell culture that was treated with PKB inhibitor.