1The presence of an amino group at position 8 of the hypoxanthine moiety stabilizes the triplex but, surprisingly, destabilizes the duplex.
2The most abundant substitution was that of proline to serine, which was disposed mainly on the three canonical DQ2.5 domains on position 8.
3Substitutions in positions 8 and 9 were without effect or were inhibitory.
Translations for position 8