Significats de positional cloning en anglès

We now describe the positional cloning of the gene mutated in EDA.

In this paper, EXT2 gene was cloned with positional cloning and homologous screening.

We describe the positional cloning of a gene encoding a novel protein, nibrin.

Further fine mapping and positional cloning are required for the identification of the Par2 gene.

The MEN1 gene was recently isolated by positional cloning.

Here, using positional cloning and bacterial artificial chromosome rescue, we show that ash encodes Rab27a.

They also provide a starting point for the identification of the affected gene by positional cloning.

Here we report the positional cloning of FANCD2.

The chicken BAC library constitutes an invaluable tool for positional cloning and for comparative mapping studies.

We have previously used positional cloning techniques to define a new putative K+-channel gene, KVLQT1.

These novel DNA markers should aid in positional cloning strategies presently employed to identify these mutant loci.

In this study, high-resolution mapping of the gene was carried out for the positional cloning of the gene.

The MEN1 gene is on chromosome 11q13; it was recently identified by positional cloning.

In positional cloning, once linkage is obtained, the gene can eventually be isolated, cloned, and sequenced and mutations identified.

Despite multiple efforts using traditional positional cloning, the causative genes for unsolved dystroglycanopathy cases have escaped discovery for several years.

Here we have used positional cloning to identify the gene responsible for the hypochromic anaemia of the zebrafish mutant weissherbst.