Significats de pseudoexfoliation en anglès

Materials and methods: Seven patients with pseudoexfoliation glaucoma were enrolled in the study.

Conclusions: Multiple Icelandic families with pseudoexfoliation in two generations were identified.

At least one individual with pseudoexfoliation was identified in the second generation of every family.

Purpose: To estimate the incidence of pseudoexfoliation (PEX) and its associated risk factors in a defined population in Sweden.

Methods: Icelandic families containing three or more members aged 70 or older with at least one member with pseudoexfoliation were identified.

These data clearly indicate that pseudoexfoliation is a familial condition and although not conclusive, supports the hypothesis that pseudoexfoliation syndrome is genetically inherited.

Although the sample size was small, no association between pseudoexfoliation affected status and cardiovascular disease, cerebrovascular disease, systemic hypertension, or diabetes mellitus was found.

We demonstrate proof of principle by clearly identifying the associated variants for eye color, age-related macular degeneration, and pseudoexfoliation syndrome in cohorts not previously studied.

Our Caucasian population has a 9-fold lower lifetime incidence of pseudoexfoliation syndrome compared with Nordic populations despite having similar allelic architecture at the LOXL1 locus.

Pseudoexfoliation was strongly associated with the presence of glaucoma, but was not associated with either ARMD or systemic disease in this study.

Materials and methods: Seven patients with pseudoexfoliation glaucoma were enrolled in the study.

Conclusions: Multiple Icelandic families with pseudoexfoliation in two generations were identified.

At least one individual with pseudoexfoliation was identified in the second generation of every family.

Purpose: To estimate the incidence of pseudoexfoliation (PEX) and its associated risk factors in a defined population in Sweden.

Methods: Icelandic families containing three or more members aged 70 or older with at least one member with pseudoexfoliation were identified.

These data clearly indicate that pseudoexfoliation is a familial condition and although not conclusive, supports the hypothesis that pseudoexfoliation syndrome is genetically inherited.