Significats de putative target en anglès

These findings support augmenting A2AR signaling as a putative target for limiting aneurysm formation.

TYR was proved as a putative target of miR-374 as the evidenced by the result.

Methods: Luciferase reporter assays were employed to validate regulation of a putative target of miR-125b.

Moreover, we analyzed sRNA-mRNA hybrids and accessed putative target genes for the novel sRNA candidates.

Crk is a predicted putative target gene for miR-126.

Our findings highlight OPNa variant as TC biomarker, besides being a putative target for cPTC therapeutic approaches.

First, each executed a radical course change, veering away from its putative target through a dizzyingly rapid, curving twist.

We identified SLC6A19 as a novel putative target gene of AhR activation in HepG2 cells.

These targets were subsequently compared with previously curated gene dataset involved in cervical cancer to derive the putative target dataset.

These studies have been limited in size, however, and have not attempted to link miR-155 expression to that of putative target genes.

The lithium-blockable enzyme inositol polyphosphate 1-phosphatase in the phospholipase C signaling pathway is a putative target for the mood-stabilizing effects of lithium.

WT1 proteins can activate and repress putative target genes in vitro, although the in vivo relevance of such target genes often remains unverified.

The level of miR-379 and its putative target Cyclin B1 were investigated on all breast tissue specimens by RQ-PCR.

We also leveraged these data to link enhancers to putative target genes and demonstrate tissue-specific enrichments of sequence variants associated with disease in humans.

The affinities of full-length hSRY and the hSRY-HMG domain for a single cisplatin-DNA adduct were comparable to those for the putative target sequence AACAAAG.

Together, our results suggest that PRKDC is a prognostic marker of poor survival and is a putative target to overcome chemoresistance in gastric cancer.