Significats de pyrimidine en anglès

Neither modulating pyrimidine metabolism nor purine salvage has similar effects.

Current clinical trials are evaluating the role of non-fluorinated pyrimidine agents in an adjuvant setting.

The resulting deuterosugar is converted into pyrimidine nucleosides and incorporated into DNA using standard protocols.

Reducing aspartate availability for pyrimidine synthesis restricted cancerous proliferation.

They are activated by both pyrimidine and purine nucleotides.

It is therefore crucial to limit thymine-replacing uracils.dUTP is constantly produced in the pyrimidine biosynthesis network.

Acetic anhydride converts the base into an acetamino-dimethyl pyrimidine, acetic acid and acetamide being also formed.

The results obtained displayed many more cross-ring fragmentation of the pyrimidine ring compared to the pyridine ring.

The pyrimidine rings are in sofa conformations.

A new series of benzothiazoles hybridized with pyrimidine moiety was designed and synthesized using the lead compound 4a.

CPS1 loss reduces the pyrimidine to purine ratio, compromises S-phase progression and induces DNA-polymerase stalling and DNA damage.

This enzyme exhibits pyrimidine-specific catalytic activity, with a marked preference for poly(C) substrate over poly(U) substrate.

Moreover, insertion of an upstream pyrimidine tract was sufficient to convert a PTB-activated exon to a PTB-repressed exon.

Adipocyte Xbp1s overexpression drives energy mobilization and protects mice from obesity through activation of the pyrimidine biosynthesis pathway.

Intracellular AMP accumulation by adenosine kinase after adenosine uptake would induce C6 cell growth inhibition through pyrimidine starvation.

Purpose: Despite more than four decades of fluoro-pyrimidine treatment in different cancers, the optimal schedule is still not known.