Significats de recapitulate human en anglès

Outstanding challenges remain to understand and reestablish EC organ specificity for in vitro studies to recapitulate human organ-specific physiology.

Complex 3D in vitro models that can recapitulate human tissue biology are essential for understanding the pathophysiology of disease.

Murine models of intestinal cancer are powerful tools to recapitulate human intestinal cancer, understand its biology and test therapies.

Linked PBTK and TD models can explore the parameter space to recapitulate human population variability in response to chemical insults.

We developed and characterized the patient-derived xenograft (PDX) model because it is likely to recapitulate human tumor biology.

Most of the knowledge on ZIKV pathogenesis was gained using immunocompromised mouse models, which do not fully recapitulate human pathology.

Organ-on-a-chip technology offers the potential to recapitulate human physiology by keeping human cells in a precisely controlled and artificial tissue-like microenvironment.

Therefore, there is a need to establish in vivo models that recapitulate human oral cancer metastasis to evaluate therapeutic potential of novel drugs.

One potential explanation for this failure lies in the lack of suitable translational models that adequately recapitulate human cardiovascular physiology and disease expression.

In addition, we will discuss how closely the baboon model recapitulates human EBOV infection.

We developed a collection of genetically modified mouse strains recapitulating human primary SND associated with different degrees of AV block.

The present study revealed new insights into the pathology of retinal ischemia using the rabbit RVO model, which accurately recapitulates human disease.

Purpose: We generated extensive transcriptional and proteomic profiles from a Her2-driven mouse model of breast cancer that closely recapitulates human breast cancer.

Thus, we have developed an in vitro model that recapitulates human hippocampus development, allowing the generation of functional hippocampal granule- and pyramidal-like neurons.