Significats de regulate kinase en anglès

Additional autophosphorylations that are both physically and functionally distinct serve to regulate kinase activity and complex dissociation.

We propose that the DHp domain of KinA transmits conformational signals to regulate kinase activity via this proline-mediated interaction.

These distinct responses likely occur via differences in extracellular signal- regulated kinase signaling in DCs.

Discovery of neo-substrates for kinases could provide a heretofore-unappreciated modality for regulating kinase activity.

Mechanistically, reactive oxygen species and extracellular signal- regulated kinase were found to mediate ADAM17 activation.

This mutation also decreased arrestin-dependent activation of extracellular signal- regulated kinases.

This event desensitizes FasL-mediated apoptosis by inhibiting extracellular signal regulated kinase activity and up-regulating NF-kappaB.

We evaluated testicular extracellular signal regulated kinase, tumor necrosis factor-alpha and interleukin-6 by Western blot.

Autophosphorylation within the kinase's activation loop regulates kinase activity.

This also means that nitric oxide synthases are regulated indirectly by the events that regulate kinases.

It has been reported that the activation of extracellular signal- regulated kinase (ERK) reduces melanin synthesis.

Inhibition of the extracellular signal- regulated kinase branch of the mitogen-activated protein kinase signaling cascade is an alternative approach.

Furthermore, excessive extracellular signal- regulated kinase and IKK kinase activities were observed in carcinomas compared with those in papillomas.

The extracellular signal- regulated kinase (ERK) signaling pathway is constitutively activated in many human tumor cell types.

Cancerous mutations in MAPK pathways are frequently mostly affecting Ras and B-Raf in the extracellular signal- regulated kinase pathway.

DNA damage-mediated activation of extracellular signal- regulated kinase (ERK) can regulate both cell survival and cell death.