Significats de renal scarring en anglès

Background: Acute pyelonephritis is distinguished from renal scarring using repeat cortical scintigraphy.

Background: Uncontrolled apoptosis contributes to tubular cell deletion in renal scarring.

There was no support for a relationship between type 1 fimbriae and renal scarring.

Apoptosis has been proposed to play an important role in the progression of renal scarring.

The non-secretor phenotype was significantly associated with the occurrence of renal scarring among patients with recurrent pyelonephritis.

Conclusions: The results identify a genetic innate immune deficiency, with a strong link to APN and renal scarring.

Finally, the mechanisms of renal scarring in IL8Rh KO mice will be discussed in relation to human disease.

In conclusion, intra renal vascular resistivity is significantly increased in recurrent UTI patients particularly in those sustaining renal scarring.

Individuals prone to UTI and renal scarring were found to be a genetically selected subgroup of the general population.

The tissue damage resembles human disease, and these mice offer a model system to study the molecular mechanisms of renal scarring.

These findings suggest that MMPs may play an important role in matrix accumulation associated with progressive renal scarring in this model.

Data are also accumulating that may soon link the degree of tubulointerstitial injury with glomerular damage and subsequent development of renal scarring.

The bacterial and host parameters combined indicate that host parameters are essential for the tendency to develop renal scarring after acute pyelonephritis.

A correlation between P1 blood group phenotype and susceptibility to UTI and between blood group non-secretor state and renal scarring was found.

Background: Recent studies have suggested that connective tissue growth factor (CTGF) plays a key role in tissue fibrosis including renal scarring.

This review summarizes recent work examining the interaction between host and parasite in recurrent urinary tract infection (UTI) and renal scarring.