Significats de repress gene en anglès

The molecular mechanisms by which JAZ proteins repress gene expression remain unknown.

The mechanisms by which steroid receptors repress gene expression are not well understood.

Our analysis suggested that PHF8 not only activates but may also repress gene expression.

Conclusions: We identify GWAS risk loci involved in long-range loops that function to repress gene expression within chromatin loops.

DNA-binding transcriptional regulators interpret the genome's regulatory code by binding to specific sequences to induce or repress gene expression.

Distinct molecular mechanisms allow lncRNAs either to activate or to repress gene expression, thereby participating in the regulation of cellular and tissue function.

Sall1 is a multi-zinc finger transcription factor that represses gene expression and regulates organogenesis.

This observation implies that TGF-beta1 might not be a truly androgen- repressed gene in these tissues.

Both pathways require the RNA-processing enzyme Dicer to produce the active small-RNA component that represses gene expression.

The 129 repressed genes showed putative roles in vesicle trafficking, signal transduction, nitrogen metabolism, or molecular transport.

Yet its in vivo site selectivity and ability to distinguish between activated versus repressed genes remain incompletely understood.

Mechanistically, we find that LSD1 enzymatically represses genes that are normally expressed only in fetal and neonatal epithelium.

N-CoR and HDAC3 are both required for recruitment of SNF2H to the repressed gene.

The repressor function of STAT6 is HDAC3 dependent on a subset of IL-4- repressed genes.

These data suggest that CHES1 recruits SKIP to repress genes important for tumorigenesis and the response to cancer treatments.

ZEB2 and T-bet cooperate to switch on a terminal CTL differentiation program, while simultaneously repressing genes necessary for central memory CTL development.