Meanings of selective ligands in anglès

These inconsistencies have most likely arisen from the unavailability of selective ligands.

Biased agonism offers an opportunity for the medicinal chemist to discover pathway- selective ligands for GPCRs.

We tested the effects of neonatal exposure to ER selective ligands and DES on female mice.

Defining a biological role for GPR55 requires GPR55 selective ligands that have been unavailable.

A current challenge is how to use this structural information for the rational design of novel potent and selective ligands.

At the extreme, functionally selective ligands may be both agonists and antagonists at different functions mediated by the same receptor.

This study demonstrates that carbohydrates can be used as selective ligands for cancer cells in a photodynamic therapy with LNP.

In the pursuit of these goals, there is currently a tendency to focus on selective ligands of "novel" nonmonoaminergic targets.

However, definition of its functions has been slowed by a dearth of selective ligands that can distinguish it from the closely related FFA3.

This method, developed to reveal the most suitable regions of isoenzymes for the design of selective ligands, also has a very practical utility.

To address the need for novel selective ligands, we synthesized two compounds potentially having FFA2 activity and examined the molecular basis of their function.

This has led to concerted efforts to find selective ligands for the glucocorticoid receptor that preserve the beneficial anti-inflammatory activity but reduce the side-effect profile.