Significats de simple fs en anglès

All affected members presented a homogeneous phenotype of simple FS.

Conclusions: Children with past simple FS showed greater changes in salivary cortisol following stress, suggesting enhanced stress sensitivity.

The absence of linkage in the third family supports genetic heterogeneity of the AD form of pure simple FS.

Future studies are needed to investigate whether stress sensitivity may be premorbid to simple FS and may contribute to simple FS incidence.

We report a clinical and genetic study of three families with simple FS segregating as an autosomal dominant (AD) trait with high penetrance.

The impact of severity of seizures was assessed by comparing the children who had prolonged FSs to 4 infants that had experienced a simple FS.

The locus mapping to 6q22-q24 seems to be the first identified locus responsible for pure simple FS, the most frequent form of FS.