Significats de skeletal phenotype en anglès

These mice did not have a skeletal phenotype, indicating that Rbpjk is dispensable for osteocyte function.

In this study, we characterized the skeletal phenotype of a mouse with targeted disruption of Pedf.

In sum, we have identified a spontaneous mutation in the Irs1 gene associated with a major skeletal phenotype.

We also examined the skeletal phenotype of transgenic mice expressing Nov under the control of the human osteocalcin promoter.

In conclusion, HeyL null mice do not exhibit an obvious skeletal phenotype demonstrating that HeyL is dispensable for skeletal homeostasis.

The skeletal phenotype is believed to result from imbalances in the hedgehog signaling pathway that normally occurs in functional cilia in chondrocytes.

Co-incidence of LEMD3 and EXT1 gene mutations was not associated with a more severe skeletal phenotype in those patients.

In conclusion, transgenic mice expressing IGFBP-5 1-162 and 1-193 in the bone microenvironment do not exhibit an obvious skeletal phenotype.

In this study, we characterized the skeletal phenotype of mice carrying a mutation in the TGF-β type 2 receptor associated with severe LDS in humans.

The skeletal phenotype of Col3.6-Nfatc2 mice of both sexes and of sex-matched littermate controls was investigated by microcomputed tomography and histomorphometry.

To investigate the actions of CHOP on bone remodeling, we examined the skeletal phenotype of chop null mice from 1 to 12 months of age.

Here, we report further analysis of the skeletal phenotypes of these mice at postnatal stages.

Skeletal phenotypes from both types of experiments had premaxillae that clustered geometrically with ancestral fossil forms instead of beaked birds.

When bred to homozygosity, most of these alleles recapitulated skeletal phenotypes reported previously for Gdf11 knockout mice, suggesting that these represent null alleles.