Significats de specific cpg en anglès

Decreased methylation of specific CpGs were found in the promoter of ANGPTL2 and allowed to discriminate age vs. disease associated methylation.

The strategy is based on the cloning of chromosome- specific CpG-rich DNA sequences which are present at the 5' end of many genes.

To identify the most robust ancestry- specific CpG sites, we replicate our results in lymphoblastoid cell lines from Yoruba African and CEPH European panels of HapMap.