Meanings of stabilize mutations in anglès

Furthermore, insights into the cooperativity between mutations allowed us to identify fold- stabilizing mutations in the CDRs.

Structural analysis reveals that Pentamer is a flexible molecule, and suggests sites for engineering stabilizing mutations.

Atomic-level structures directed the application of prefusion- stabilizing mutations that improved expression and immunogenicity of betacoronavirus spike proteins.

These mutations were destabilizing, and were preceded or accompanied by stabilizing mutations that alleviated their adverse effects.

Our results paint a coherent portrait of epistasis during nucleoprotein evolution, with stabilizing mutations permitting otherwise inaccessible destabilizing mutations which are sometimes of adaptive value.