Significats de structural motif en anglès

The functional role of this structural motif has been demonstrated by point mutagenesis, including compensatory mutations.

Evidence is presented to show that the structural motif responsible for the inhibition is the amphipathic alpha-helix.

Zinc fingers are a protein structural motif that serve as DNA-binding domains in several transcriptional regulatory proteins.

Deletion of a critical structural motif disrupts tetramer formation and results in loss of Vps74p localization and function.

The structure reveals that the eight PUM repeats correspond to eight copies of a single, repeated structural motif.

Apicoplast TPs do not contain a conserved sequence motif; therefore, we asked whether they contain an essential structural motif.

The widespread targeting of voltage-sensor paddles by toxins demonstrates that this modular structural motif is an important pharmacological target.

We conclude that the iridals represent a promising structural motif for design of ligands for phorbol ester receptor family members.

It has been proposed that these drugs bind to the Na+ channel pore with a common diphenyl structural motif.

The ladder-like structural motif thus formed is extended into one-dimensional polymeric chains by virtue of bridging bidentate mode of the sulfonate groups.

This 90 degrees structural motif is persistent both in solution and in the solid state, which allows the one-step formation of tetrasulfonamide macrocycles.

Based on the simple repetition of the same structural motif and local conformational preference, undecamer 2 was found to fold into well-defined helical conformation.

It is suggested that this structural motif and the mode of binding can be realized during interaction of CTXs with lipid and biological membranes.

The structure clearly resembles the inhibitor cystine knot structural motif, although the triple-stranded beta-sheet typically found in that motif is partially distorted in Magi 5.

Oligoamide strands containing tertiary amide groups were found to share a basic structural motif that promotes the formation of H-bonded, chain- or tape-like supramolecular assemblies.

The most prominent structural motif of the P4-P6 domain is the tetraloop-tetraloop receptor interaction which "clamps" the distal parts of its hairpin-like structure.