Significats de sulfonamides en anglès

A series of amino-caprolactam sulfonamides were developed from a screening hit.

Amide-sulfonamides provide a potent anti-inflammatory scaffold targeting the CXCR4 receptor.

Eight of the 10 patients with previous adverse reactions to sulfonamides had slow acetylator phenotypes.

Piperidinyl diphenylsulfonyl sulfonamides are a novel class of molecules that have inhibitory binding affinity for sFRP-1.

In this study, we present the design and synthesis of novel gallium-radiolabeled small-molecule sulfonamides targeting CA IX.

This structural characteristic was observed in molecules with distinct antibacterial activities, demonstrating a clear structureactivity relationship of sulfonamides.

A series of 4-amino-6-methyl-1,3,5-triazine sulfonamides were synthesized and evaluated as inhibitors of PI3K.

Conclusion: This short review sought to contextualise the discovery of classic antibacterial sulfonamides and their physico-chemical and pharmacological properties.

We have previously synthesized a series of 7-aroylaminoindoline-1-sulfonamides as a novel class of antitubulin agents.

We have discovered a novel class of heterocyclic sulfonamides that act as antagonists of the S1P1 receptor.

Rubreserine appeared to be more efficient than sulfonamides, antifolate drugs known to inhibit the invasion and proliferation of T. gondii in human fibroblasts.

Novel sulfa Schiff bases were synthesized and characterized by a reaction between aromatic sulfonamides and aromatic aldehydes or heterocyclic ketones in equimolar ratios.

In addition, the elimination of SO 2 through a three-membered-ring transition state followed by the formation of C-N was observed for all the amide-sulfonamides.

Discussion: The synthesis of sulfonamides is considered to be simple and provides a diversity of derivatives from a wide variety of amines and sulfonyl chlorides.

The purpose of this study was to summarize the clinical findings in 40 dogs with systemic hypersensitivity reactions associated with the administration of potentiated sulfonamides.

Sulfonamides were the most prevalent antibiotics, and the concentrations of antibiotic in sediments were higher than those in water.