During postnatal development, sympatheticinnervation of the heart evolves, and repolarization accelerates.
2
The expression of the chemorepellent Sema3a is inversely related to sympatheticinnervation.
3
Background: Heterogeneity of sympatheticinnervation is thought to contribute to the potential for fatal arrhythmia.
4
Horner's syndrome results from a unilateral disruption of the sympatheticinnervation to the head and neck.
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Our goal in this study was to test whether sympatheticinnervation modulates the ion channels that regulate repolarization.
6
Here, we report the developmental loss of sympatheticinnervation in human Down syndrome organs and in a mouse model.
7
Tyrosine hydroxylase staining in fetal and postnatal kidneys revealed that sympatheticinnervation of renin-producing cells occurs early in fetal development.
8
Owing to the presence of incomplete reinnervation, heart transplant recipients provide a unique model to study the effects of efferent sympatheticinnervation.
9
Our results suggest that sympatheticinnervation contributes to the developmental differences in K+ currents and APD postnatally in the rat.
10
Therefore, we investigated whether the decreased TH-IR fiber density is the consequence of reduced sympatheticinnervation, or a decrease in TH expression within innervating fibers.
11
This shows that the onset of extrinsic sympatheticinnervation is regulated by the developmental stage of the animal rather than by adaptation to extrauterine life.