Electrophoretic mobility-shift assays demonstrated that it bound to the tissue-restricted transcriptionfactorGATA-1.
2
The nuclear protein FOG-1 binds transcriptionfactorGATA-1 to facilitate erythroid and megakaryocytic maturation.
3
The transcriptionfactorGATA-1 plays a significant role in erythroid differentiation and association with CBP stimulates its activity by acetylation.
4
The transcriptionfactorGATA-1 is required for terminal erythroid maturation and functions as an activator or repressor depending on gene context.
5
The transcriptionfactorGATA-2 is expressed in hematopoietic stem and progenitor cells and is functionally implicated in their survival and proliferation.
6
Here we review the participation of zinc finger transcriptionfactorGATA-2 in regulating normal hematopoietic stem and progenitor cell functionality, myelodysplasia and myeloid leukemia.
7
The transcription factor endothelial transcriptionfactorGATA-2 (GATA2) has been reported to have a key role in driving prostate cancer aggressiveness.