Encara no tenim significats per a "unacceptable toxicity".
1Therapy was continued until evidence of disease progression or unacceptable toxicity occurred.
2Treatment was stopped early in both arms for progressive disease or unacceptable toxicity.
3Patients received oral ibrutinib 420 mg once daily until progression or unacceptable toxicity.
4Patients continued receiving sorafenib until disease progression or unacceptable toxicity occurred.
5There were no treatment-related deaths and no patient encountered unacceptable toxicity.
6Treatment cycles were repeated until disease progression, patient's refusal or unacceptable toxicity occurred.
7Treatment continued until there was documented disease progression or unacceptable toxicity.
8Cycles were repeated until disease progression, unacceptable toxicity or patient refusal.
9The 28-day cycle was repeated until there was unacceptable toxicity or disease progression.
10Pertuzumab and trastuzumab were administered until disease progression or unacceptable toxicity.
11Treatment was continued until disease progression or unacceptable toxicity for up to 12 months.
12Treatment was continued until progression, unacceptable toxicity, or patient refusal.
13Treatment was continued until disease progression or unacceptable toxicity occurred.
14Patients remained on study until disease progression or unacceptable toxicity.
15Treatment was repeated until disease progression or unacceptable toxicity occurred.
16Treatment continued until disease progression by RECIST or unacceptable toxicity.
Aquesta col·locació està formada per:
Unacceptable toxicity a través del temps
Unacceptable toxicity per variant geogràfica