Significats de urinary exosomes en anglès

Herein is described the advantages of using urinary exosomes as a starting material for biomarker discovery.

Our results revealed an abundant expression of the four candidate miRNAs in urinary exosomes and no detectable expression of RNU6B.

A low-sodium diet also increased pNCC in urinary exosomes approximately 1.5-fold after 4 and after 8 days of treatment.

For this purpose, miRNA expression levels were determined by RT-qPCR after the isolation of urinary exosomes from 33 CKD patients and from 5 healthy controls.

Urinary exosomes were isolated from 24-hour urine or spot urine using ultracentrifugation.

Urinary exosomes are vesicles derived from renal tubular epithelial cells.