Significats de vestibular aqueduct en anglès

Cochleo-vestibular malformations and large vestibular aqueduct are the 2 most frequent deformities.

Results suggest that all ears with a large vestibular aqueduct have associated cochlear modiolar deficiencies.

Furthermore, shorter relaxation times were measured for the contents of the vestibular aqueduct than for other labyrinthine structures.

Loss-of-function and hypo-functional mutations cause an enlargement of the vestibular aqueduct (EVA) and sensorineural hearing loss.

Objective: Defects of the cochlear modiolus have been found to be associated with most cases of large vestibular aqueduct.

Thus, a large vestibular aqueduct may be only occasionally, if ever, an isolated developmental anomaly of the inner ear.

However, the thickness and morphology of the vestibular aqueduct may simply be markers for more subtle cochlear dysplasia manifest by modiolar deficiency.

Mutations of SLC26A4 are a common cause of human hearing loss associated with enlargement of the vestibular aqueduct.

SLC26A4 mutations cause fluctuating and progressive hearing loss associated with enlargement of the vestibular aqueduct (EVA).

Enlargement of the vestibular aqueduct (EVA) is the most common inner ear anomaly detected in ears of children with sensorineural hearing loss.

Conclusions: These observations support the hypothesis that large vestibular aqueduct-related hearing loss may be caused by transmission of subarachnoid pressure forces into the inner ear.

Vestibular aqueduct morphology and thickness correlated very strongly with the severity of hearing loss.

Patients: Thirty consecutive patients with large vestibular aqueducts participated.