Brown and whiteadipocytes have been shown to derive from different progenitors.
2
We conclude angiotensinogen expression in whiteadipocytes is regulated nutritionally in a tissue-specific manner.
3
The browning of the whiteadipocytes involved increased norepinephrine release from the sympathetic nervous system.
4
Interestingly, mature whiteadipocytes are integrated into several tissues.
5
We also demonstrated that miRNAs are essential for the browning of subcutaneous whiteadipocytes in vitro and in vivo.
6
Taken together, the data bring to light an intriguing divergence between whiteadipocytes of the mouse and other mammalian species.
7
Conclusions: This work uncovers novel pathways regulated by PGC-1 alpha and reveals that PPARalpha controls gene expression in human whiteadipocytes.
8
Together with dWAT's dynamic responses to external stimuli, we established that dermal adipocytes are a distinct class of whiteadipocytes with high plasticity.
9
We hypothesized that 10E,12Z-CLA impairs lipid storage in adipose tissue by altering the lipid metabolism of whiteadipocytes.
10
It is still not fully understood whether these cells differentiate de novo from specific progenitor cells or if they transdifferentiate from mature whiteadipocytes.
11
PM20D1 is a candidate thermogenic enzyme in mouse fat, with its expression cold-induced and enriched in brown versus whiteadipocytes.
12
Whiteadipocytes are plastic cells able to reversibly transdifferentiate into brown adipocytes and into epithelial glandular cells under physiologic stimuli in vivo.