Significats de wingless signaling en anglès

Where appropriate, wingless signaling will be compared to the activity of vertebrate Wnt proteins.

Well-described subgroups of medulloblastomas include tumors showing wingless signaling pathway (Wnt) activation, and another characterized by sonic hedgehog pathway activity.

We propose that at least one of the functions of Drosophila Tel2 is regulation of Wingless signaling.

In Drosophila, Wingless signaling mediates endoderm induction and the establishment of segment polarity in the developing embryo.

Maximal Wingless signaling suppresses cellular proliferation.

We show that Atg6 is required for the downregulation of Notch and Wingless signaling pathways; thus it is essential for normal wing development.