Significats de xenobiotics en anglès

These findings show that mammalian kidney is highly active in bioactivation of xenobiotics.

Filter-feeding organisms accumulate xenobiotics and other substances in their tissues.

Primary hepatocytes are a model for studying various effects of different xenobiotics, including detoxification strategies.

Prediction of response to environmental stimuli, xenobiotics and diet.

Additionally, it has long been appreciated that exposure to drug metabolism-inducing xenobiotics can impair immune function.

Recent studies have demonstrated that endogenous chemicals are also oxidized by human P450s which mainly metabolize xenobiotics.

There is a wide promiscuity of these receptors in the induction of CYPs in response to xenobiotics.

Adverse effects of xenobiotics reported earlier might be camouflaged by beneficial eel constituents, such as n-3 fatty acids.

The cytochrome P450 enzymes are highly expressed in the liver and are involved in the metabolism of xenobiotics.

The molecular functions of these genes have been associated with the metabolism of lipids and detoxification of xenobiotics.

Our understanding of ocular toxicities from xenobiotics in humans, livestock, and wildlife is growing thanks to laboratory animal models.

Polymorphism of MDR1 gene is connected with reduction of P-glycoprotein expression in placenta and increased fetal exposure to xenobiotics.

It is unknown whether AEA can influence fetal concentrations of xenobiotics by modulating the expression of transporters in syncytiotrophoblasts.

This result is supported by studies that show glutathione conjugation of some xenobiotics by the GSTs can produce mutagenic intermediates.

Such a multi-analytical approach will potentially provide an information-rich platform for the elucidation of effects of xenobiotics and drug efficacy studies.

As a consequence of mutations in the genes coding for transmembrane protein pumps, the intracellular concentration of xenobiotics may significantly increase.