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We show, herein, that the liprin-a1 protein is highly expressed in human breast tumors.
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We recently demonstrated that liprin-a1 is an important regulator of cell edge dynamics during motility.
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The PPFIA1 gene for liprin-a1 is frequently amplified in human breast cancers.
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Our results strongly support a novel important role of liprin-a1 in the regulation of human tumor cell invasion.
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We have previously identified the scaffold protein liprin-a1 as an important regulator of integrin-mediated cell motility and tumor cell invasion.
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We used time-lapse analysis to demonstrate defects in the motility of liprin-a1-depleted cells that include a striking instability of the lamellipodia.
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You'll also tell these apart from other A1's by their red calipers.
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Flying into Edinburgh or coming north on the A1: there they are.
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Discontinuation of A1-AR induction mitigated cardiac dysfunction and significantly improved survival rate.
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I think I got my A, but an A1 is another matter.
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That's more expensive than some foreign brands such as the Audi A1.
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A section of the main A1 was sealed off overnight but reopened today.
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She got the best results in the school - seven A1s.
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The new A1 is the most accessible vehicle in the German brand's line-up.
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And I love this A1's chunky front end and intricate, twinkling LED lights.
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We were soon heading south towards Peterborough and onto the A1.