Meanings of acting antivirals in English

Treatment as prevention with highly effective new direct- acting antivirals is a prospective HCV elimination strategy.

An improved CoC along with new direct- acting antivirals should help to decrease chronic HCV infection.

Direct- acting antivirals might overcome factors such as immunodeficiency that can reduce the efficacy of IFN.

The association between direct- acting antivirals and these outcomes was quantified using time-dependent Cox proportional hazards models.

Currently, second generation direct acting antivirals (DAAs) promise clearance of infection in most of patients.

Trials employing combinations of direct- acting antivirals that include NS5A inhibitors have shown significant promise in meeting this challenge.

We enrolled 472 patients with chronic HCV infection who achieved viral eradication with direct- acting antivirals (DAA).

Hepatitis C viral treatment has dramatically advanced with the FDA approval of several new agents known as direct- acting antivirals.

Several other newer direct acting antivirals have shown promise in clinical studies and are likely to be licensed soon.

The introduction of HCV direct- acting antivirals (DAA) holds the potential to improve clinical outcomes also in inmates.

Here, we assessed factors associated with increased-risk donor liver transplant and determined their impact on survival and response to direct- acting antivirals.

We are now reporting three cases of intrahepatic cholangiocarcinoma that developed after sustained virologic response following hepatitis C viral treatment with direct- acting antivirals.

This work highlights a new method for the discovery and optimization of direct- acting antivirals targeting the E protein of Zika and other flaviviruses.

With advances in cell culture systems over the past decade, the development of directly acting antivirals (DAAs) for HCV has become possible.

The first direct- acting antivirals have recently been approved, and combination all-oral therapy (interferon free) is expected in 3-5 years.

Treatment with direct- acting antivirals was initiated during follow-up in 7344 patients, and 2551 patients remained untreated at the final follow-up visit.