Meanings of activate stat in English

This region contains a STAT response element, and GO activates STAT-3 binding to this STAT response element.

Recent examinations suggest that activated STAT signalling participates in oncogenesis by stimulating cell proliferation and preventing apoptosis.

These events were preceded by an arsenic trioxide dose-dependent down-regulation of activated STAT proteins starting at 6 hours.

We observed differences in their signaling properties: they both activated STAT, whereas AKT was only activated by ECD mutants.

The PIAS proteins (protein inhibitor of activated STAT) were originally identified as inhibitors of the JAK-STAT pathway.

Anti-IL-6R-treated reconstituted SCID mice showed decreased levels of activated STAT-3.

Deregulated STAT activity is often found associated with tumorigenesis and activated STATs seem to be limiting components in tumor cells.

Taken together, these results suggest that leptin, by activating STAT-3, may act as a paracrine factor modulating mammary epithelial cell function.

Members of the PIAS (for protein inhibitor of activated STAT) family play critical roles in modulating the activity of a variety of transcriptional regulators.