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The goal of this study was to determine if the sensitization induced by ET-1 priming is occurring at the level of the primary afferentneuron.
2
At the level of the primary afferentneuron, ET-1 priming has a desensitizing effect on challenge exposures to ET-1 and capsaicin.
3
The behavioral effects would be paralleled by changes in response properties of primary afferentneurons.
4
Afferentneurons in the DRGs that innervated the joints were identified using retrograde fluorogold labeling.
5
Substance P is a neuropeptide released by afferentneurons in the respiratory tract during inflammatory reactions.
6
This effect was reversed by administration of SP to anti-CD95 mAb-treated mice depleted from primary afferentneurons.
7
Glandular secretion is regulated through a neural reflex initiated by trigeminal primary afferentneurons innervating the corneal epithelium.
8
Previously, we have shown that primary afferentneurons are necessary for disease activity in immune-mediated liver injury in mice.
9
The dorsal column nuclei (DCN) of the brain stem contain secondary afferentneurons, which process ascending somatosensory information.
10
These data indicate that NO has functional actions on centrally projecting rat vagal afferentneurons that ultimately innervate the NTS.
11
A natural way to determine limb state is to measure and decode the activity of primary afferentneurons in the limb.
12
Preliminary data indicate that the vagal afferentneurons express several S1P receptors including S1PR 2-3 .
13
In contrast, mild cooling of the ocular surface has been reported to increase lacrimation via activation of corneal cool primary afferentneurons.
14
We found that expression of mOR mRNA and protein in primary afferentneurons changed dynamically and site-specifically following L5 spinal nerve ligation.
15
The proteinase-activated receptor 2 is expressed on a subset of primary afferentneurons and may participate in the neurogenic component of inflammation.
16
Background: Visceral pain is initiated by activation of primary afferentneurons among which the capsaicin-sensitive (TRPV1-positive) neurons play an important role.