The aforementioned results on OS were also replicated during the examination of relapse-free survival.

Knockdown of FKBP11 by transfection with small interfering RNA further validated the aforementioned results.

All the aforementioned results did not change when the researchers only considered women using the Copper 7 IUD.

The aforementioned results provide further evidence for the developmental basis of amyloidogenesis and late-life disturbances in AD-associated proteins by environmental agents.