Classical alchemical doctrine teaches that it also has dominion over another province: change.

At a later time the idea helped to establish the alchemical doctrine that sulphur and mercury are the Principles of all things.

At any rate, the development of alchemical doctrine can be seen to have proceeded concomitantly with the development of mystical philosophy and theology.

In all the alchemical doctrines mystical connections are evident, and mystical origins can generally be traced.