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Meanings of alkylators in English
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning.
Usage of alkylators in English
1
HDAC inhibitors, DNA alkylators and nucleoside analogs are effective components of combination chemotherapy.
2
On the other hand, the use of alkylators and topoisomerase II inhibitors is associated with an increased risk of t-AML.
3
The protein level of MRP1 correlated with cellular resistance to busulfan and chlorambucil, and Rom exposure sensitized cells to these DNA alkylators.
4
To determine a possible mechanism of their synergism, we analyzed the effects of HDAC inhibitors on the expression of drug transporters which export DNA alkylators.
Alkylators through the time