This morphologic effect was associated with an augmented motor response to amphetamine.

Unexposed subjects were matched, denied amphetamine use, and had negative meconium screens.

Still, D-amphetamine was associated with increased alertness on the first recovery day.

Emergence of neuronal pathology was temporally associated with emergence of amphetamine-induced hyperlocomotion.

The same behavior was observed for amphetamine-methamphetamine and for two methylenedioxyamphetamine derivatives.