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1
DNA analysis showed no abnormalities in the beta
amyloid
precursor
protein gene.
2
Levels of cortical beta-
amyloid
precursor
protein were not significantly affected by drug treatment.
3
In addition, beta-
amyloid
precursor
protein staining indicated impaired axonal transport.
4
Mutations in genes such as those encoding
amyloid
precursor
…
5
The β-site
amyloid
precursor
protein-cleaving enzyme BACE1 is a prime drug target for Alzheimer disease.
6
The function of the
amyloid
precursor
protein (APP) in brain health remains unclear.
7
A functional candidate gene in this region is the beta-
amyloid
precursor
protein (APP) gene.
8
Spheroids demonstrated increased immunoreactivity to
amyloid
precursor
protein and neurofilament indicating probable impairment of axonal transport.
9
These include the
amyloid
precursor
protein and presenilins that are intimately involved in the mechanisms of AD.
10
The amyloidogenic processing of
amyloid
precursor
protein was also reduced, indicating that TUDCA interferes with Aβ production.
11
However, deposits of human-sequence Aβ in
amyloid
precursor
protein transgenic mice and non-human primates bind very little PIB.
12
Various lengths of Aβ peptide are generated by proteolytic cleavages of the
amyloid
precursor
protein (APP).
13
Beta-
amyloid
precursor
protein (betaAPP) deposits were detected within the neuronal cytoplasm from 4 months of age onward.
14
Human beta-
amyloid
precursor
protein (APP) transgenic mice are commonly used to test potential therapeutics for Alzheimer's disease.
15
The
amyloid
precursor
protein (APP) has garnered considerable attention due to its genetic links to Alzheimer's disease.
16
The
amyloid
precursor
protein (APP) has been extensively studied because of its association with Alzheimer's disease (AD).
amyloid
precursor
amyloid