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Introduction: We are witnessing an alarming increase in the burden and range of mosquito-borne arboviraldiseases.
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Background: Dengue, one of the most important arboviraldiseases of humans, may cause severe systemic disease.
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The global burden of arboviraldiseases and the limited success in controlling them calls for innovative methods to understand arbovirus infections.
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Discussion: This study will serve as a foundation for further understanding of mosquito saliva immunity and its impact on Aedes-transmitted arboviraldiseases endemic to Cambodia.